Archive for October, 2008

Extra Cash From Government Program Linked To Higher Risk Of Adult Obesity

Sunday, October 26th, 2008

While a poverty-alleviation program launched by the Mexican government that has been modeled in the United States and around the world has led to improved health and cognition outcomes in children, a new study by University of California, Berkeley, researchers says that the cash component of the program has a downside for adults.

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Addrenex Pharmaceuticals Initiates Phase 2 Trial On Its Novel Hypertension Drug, ADX415

Sunday, October 26th, 2008

Addrenex Pharmaceuticals announced that the U.S. Food and Drug Administration has approved its Investigational New Drug Application (IND) for ADX415, a novel hypertension drug. With the approval, Addrenex has launched a phase 2 clinical trial to study ADX415 as a targeted therapy for hypertension. The phase 2 trial is a multicenter, double-blind, placebo-controlled, dose-ranging study that will involve 80 patients.

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Study Finds “Rotten Egg” Gas Key To Lowering Blood Pressure

Sunday, October 26th, 2008

An international research team, with scientists from the University of Saskatchewan, has discovered that a gas produced in blood vessels regulates and lowers blood pressure. The team’s findings, based on research in mice, may one day be used to design drug therapies for controlling high blood pressure in humans.

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Sciele Pharma Announces That Addrenex Pharmaceuticals Initiates Phase II Clinical Trial Of ADX415 For The Treatment Of Hypertension

Sunday, October 26th, 2008

Sciele Pharma, Inc., a Shionogi Company, today announced that Addrenex Pharmaceuticals, Inc. has initiated its Phase II clinical trial with ADX415 for the treatment of hypertension. This is a multicenter, double-blind, randomized, placebo-controlled, dose-ranging study that will involve 80 patients. ADX415 is a novel, patented, centrally acting, alpha-adrenergic receptor agonist, specific to Alpha-2 receptors.

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Poor Perioperative Blood Pressure Control Linked To 30-Day Morbidity And Mortality In Cardiac Surgery Patients - New Analysis From The ECLIPSE Trial

Sunday, October 26th, 2008

The Medicines Company (NASDAQ: MDCO) announced that poor blood pressure control during cardiac surgery is associated with a higher risk of 30-day death, stroke, myocardial infarction and renal dysfunction, compared to patients with tight blood pressure control, according to a post-hoc analysis of the ECLIPSE trial. The data were presented at the American Society of Anesthesiologists (ASA) 2008 Annual Meeting.

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Fart Gas Helps Control Your Blood Pressure

Sunday, October 26th, 2008

Anyone with a nose knows the rotten-egg odor of hydrogen sulfide, a gas generated by bacteria living in the human colon. Now an international team of scientists has discovered that cells inside the blood vessels of mice - as well as in people, no doubt - naturally make the gassy stuff, and that it controls blood pressure.

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New Steps Uncovered On Pathway To Enlarged Heart

Sunday, October 26th, 2008

Researchers have new insight into the mechanisms that underlie a pathological increase in the size of the heart. The research, published by Cell Press in the October 24th issue of the journal Molecular Cell, may lead to the development of new strategies for managing this extremely common cardiac ailment that often leads to heart failure.

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New Book Extols Benefits Of Chocolate

Monday, October 20th, 2008

From Halloween through Valentine’s Day, chocolate helps celebrate the season. While overindulging leads to calorie concerns, the right amounts of the right kinds of chocolate can actually make one feel and even look better. Registered dietitians Shara Aaron and Monica Bearden, authors of CHOCOLATE - A HEALTHY PASSION (Prometheus Books), can explain chocolate’s role in health and wellness, as well as its history, culture, sensory pleasures and more.

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Hypertension Disparity Linked To Environment

Monday, October 20th, 2008

Social environment may play a greater role in the disparity between the numbers of African Americans living with hypertension compared to non-Hispanic whites with the disease. A study by researchers at the Johns Hopkins Bloomberg School of Public Health found that the disparity was substantially reduced when comparing groups of African Americans and non-Hispanic whites living in similar social environments.

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Fighting Obesity, Hypertension, Diabetes And Other Metabolic Diseases By Computer

Sunday, October 19th, 2008

Scientists know that different normal and diseased tissues behave differently. But a method that tells them just how they do so may one day give medical science a new way to fight obesity, hypertension, diabetes and other dangerous disorders of the metabolism. Until now, scientists had to rely on basic observations at the cellular level, since they lacked information about the metabolic processes of individual organs, such as the liver, heart and brain.

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